Even when I was a little kid, I always said I would be in the movies one day, and damned if I didn't make it.
(Just to give you an idea, Proust's reply was 'To be separated from Mama.') I think that the lowest depth of misery ought to be distinguished from the highest pitch of anguish. In the lower depths come enforced idleness, sexual boredom, and/or impotence. At the highest pitch, the death of a friend or even the fear of the death of a child.