I may not here omit those two main plagues, and common dotages of human kind, wine and women, which have infatuated and besotted myriads of people. They go commonly together.

Summary

This quote suggests that wine and women are the two main vices that have ensnared and deluded countless individuals throughout history. The author implies that these two temptations tend to be found in conjunction with one another. The phrase "infatuated and besotted" conveys the idea that people have become excessively and foolishly obsessed with indulging in wine and the company of women, leading to their downfall.

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