Minds, like bodies, will often fall into a pimpled ill-conditioned state from mere excess of comfort, and like them, are often successfully cured by remedies in themselves very nauseous and unpalatable.

Summary

This quote suggests that both the mind and body can become lazy and unfit when they experience excessive comfort. Just as bodies can be cured with unpleasant remedies, the same applies to minds. The quote implies that sometimes, to improve the state of our minds, we need to go through uncomfortable or unpleasant experiences that act as remedies. Like popping a pimple, these remedies might not be pleasant, but they can ultimately lead to a healthier and better-conditioned mind.