It is a fair, even-handed, noble adjustment of things, that while there is infection in disease and sorrow, there is nothing in the world so irresistibly contagious as laughter and good humour.

Summary

This quote suggests that although diseases and sorrows can spread and infect people, nothing spreads as easily and is as contagious as laughter and good humor. It implies that laughter and positivity have the power to uplift and influence others more profoundly than negativity. It highlights the therapeutic and uplifting nature of humor, implying that it can help counteract the negative effects of disease and sorrow by promoting joy and positivity.