Summary
This quote suggests that it is unwise to engage in conflict or opposition with an individual who lacks any stake or investment in the outcome. When someone has "nothing to lose," they are often fearless, willing to take extreme measures, and less concerned about consequences. Such individuals can be unpredictable and more dangerous since they have little or no regard for personal losses or damages. Therefore, it is often wiser to avoid confrontations with people who have nothing to lose, as the potential risks and adverse consequences are likely to be greater.