Summary
This quote, said by Lady Macbeth in Shakespeare's play Macbeth, encourages one to find the strength and determination to face difficult challenges or situations head-on. "Screw" can be interpreted as "fasten tightly" and "courage" refers to bravery or fortitude. "The sticking-place" implies the point of resistance or the location where one needs to hold steadfastly. Lady Macbeth urges herself and others to find the resolve within themselves and firmly anchor their courage in order to confront and overcome obstacles or fears.