As a small boy Francis Crick had been haunted by a fear that by the time he grew up everything would have been discovered. Inspired by Arthur Mee

Pain: an uncomfortable frame of mind that may have a physical basis in something that is being done to the body, or may be purely mental, caused by the good fortune of others

Ambrose Bierce

Most people get a fair amount of fun out of their lives, but on balance life is suffering, and only the very young or very foolish imagine otherwise

George Orwell

Let me tell you what a writer is. A writer takes comprehensive views, holds large convictions, makes wide generalizations. A writer's not English, Mexican, or American. A writer's not a woman nor a man. A writer's not Christian, Jew, Buddhist, Muslim, nor snake worshipper. To local standards of right and wrong a writer's civilly indifferent. In the virtues, a writer's concerned only with general expediency. A writer doesn't waste time focusing on fixed moral principles that aren't yet before the court of conscience. Happiness discloses itself to a writer as the end and purpose of life, and art and love are the only means to a writer's happiness. A writer is free of all doctrines, theories, etiquettes, and politics. To a writer, a continent doesn't seem long, nor a century wide. And a writer has ever present consciousness that this is a world of...fools and rogues, blind with superstition, tormented with envy, consumed with vanity, selfish, false, cruel, cursed with illusions, and frothing mad.

Ambrose Bierce

The most destructive thing we can possibly do in life is to make another person doubt his worth and identity as a child of God. The very most productive thing we can do is to help ourselves and others realize that as children of God, our worth is infinite.

Toni Sorenson

Liberty is one of the most precious gifts which heaven has bestowed on man; with it we cannot compare the treasures which the earth contains or the sea conceals; for liberty, as for honor, we can and ought to risk our lives; and, on for the other hand, captivity is the greatest evil that can befall man.

Miguel de Cervantes

Leisure and curiosity might soon make great advances in useful knowledge, were they not diverted by minute emulation and laborious trifles.

Samuel Johnson

Therefore I would ask you to write all kinds of books, hesitating at no subject however trivial or however vast. By hook or by crook, I hope that you will possess yourselves of money enough to travel and to idle, to contemplate the future or the past of the world, to dream over books and loiter at street corners and let the line of thought dip deep into the stream.

Virginia Woolf

Forget about the consequences of failure. Failure is only a temporary change in direction to set you straight for your next success.

Denis Waitley

William James used to preach the will-to-believe. For my part, I should wish to preach the will-to-doubt. None of our beliefs are quite true; all at least have a penumbra of vagueness and error.

Bertrand Russell

Scruples, temptations, and fears, and cutting perplexities of the heart, are often the lot of the most excellent persons.

Thomas Kempis

So shall I fight, so shall I tread,In this long war beneath the stars;So shall a glory wreathe my head,So shall I faint and show the scars,Until this case, this clogging mould,Be smithied all to kingly gold.

John Edward Masefield, The Creed

The value and utility of any experiment are determined by the fitness of the material to the purpose for which it is used, and thus in the case before us it cannot be immaterial what plants are subjected to experiment and in what manner such experiment is conducted.

Gregor Mendel