Nature abhors a vacuum. When a head lacks brains, nature fills it with conceit.

Summary

This quote suggests that when someone lacks intelligence or reasonable thinking, they become filled with excessive pride and self-importance. Using the metaphor of nature abhorring a vacuum, it implies that empty-mindedness will inevitably be replaced by arrogance and self-conceit. This highlights the notion that an absence of intellect creates a void that is readily inhabited by vanity and an exaggerated sense of one's own abilities or qualities.

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