I want to go out at the top, but the secret is knowing when you're at the top, it's so difficult in this business, your career fluctuates all the time, up and down, like a pair of trousers.

While the Environmental Genome Project does not seek to assign allele frequencies, we are aware of the importance of accurate allele frequency estimates for future epidemiologic studies and the large sample sizes such estimates will require.

Samuel Wilson

I think sometimes all you need is to hear someone else say the same thing that you're going through to realize that you're not alone. I try to put some sense of hope into the songs, into whatever the situation is so that it's not just dirt, drudgery and a life of misery.

Sarah McLachlan

The poet exposes himself to the risk. All that has been said about poetry, all that he has learned about poetry, is only a partial assurance.

A. R. Ammons

If you want to make beautiful music, you must play the black and the white notes together.

Richard Milhous Nixon

The ugliest thing in the world is a beautiful woman without the brains or courage to know that [beauty] is nothing more than an accident.

Charlie Fletcher

My mother and stepfather were married 43 years, so I have watched a long marriage. I feel like I had a very good role model for that. And, you know, it's just a number.

Jamie Lee Curtis

Leave this hypocritical prating about the masses. Masses are rude, lame, unmade, pernicious in their demands and influence, and need not to be flattered, but to be schooled. I wish not to concede anything to them, but to tame, drill, divide, and break them up, and draw individuals out of them.

Ralph Waldo Emerson

I always say that the real success of Wine Library wasn't due to the videos I posted, but to the hours I spent talking to people online afterward, making connections and building relationships.

Gary Vaynerchuk

Sex is like washing your face - just something you do because you have to. Sex without love is absolutely ridiculous. Sex follows love, it never precedes it.

Sophia Loren

Blessed are they who have the gift of making friends, for it is one of God's best gifts. It involves many things, but above all, the power of going out of one's self, and appreciating whatever is noble and loving in another.

Thomas Hughes

Erotica is simply high-class pornography; better produced, better conceived, better executed, better packaged, designed for a better class of consumer.

Andrea Dworkin

Men are apt to prefer a prosperous error to an afflicted truth.

Jeremy Taylor